Outbreak Update: Since the last brief (20 October 2020), 3,025,116 new confirmed coronavirus disease 2019 (COVID-19) cases and 40,780 new deaths have been reported globally. To date, a total of 42,977,875 COVID-19 cases and 1,152,8883 related deaths (case fatality rate (CFR): 2.7%) have been reported from 219 countries and territories. This week, no new country or territory reported its first case.