Outbreak Update: Since the last brief (17 November 2020), 4,123,778 new confirmed coronavirus disease 2019 (COVID-19) cases and 68,185 new deaths have been reported globally. To date, a total of 58,436,142 COVID-19 cases and 1,385,469 related deaths (case fatality rate (CFR): 2.4%) have been reported from 221 countries and territories. This week, no new country or territory reported its first case.